Thermo Fisher Scientific Endothelin 1 Monoclonal Antibody (3G10)
Endothelin 1 단백질을 인식하는 Rat monoclonal antibody (Clone 3G10). IHC(F) 및 IRMA에 사용 가능하며, 인간 시료에 반응. 단기 4°C, 장기 -20°C 보관. Protein G 정제, 1 mg/mL 농도, PBS + 0.1% sodium azide 용액.
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Applications
Immunohistochemistry (Frozen) (IHC (F))
- Assay-dependent
Immunoradiometric Assay (IRMA)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rat / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3G10 |
| Immunogen | Synthetic peptide corresponding to the C-terminal region of human endothelin (C,H,L,D,I,I,W), conjugated to BSA |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_931678 |
Product Specific Information
- For IHC applications, frozen sections processed with dry acetone are recommended.
- Paraformaldehyde is not recommended as it destroys the epitope.
- Rat anti-human endothelin antibody, clone 3G10 reacts with the C-terminal of endothelins 1, 2, and 3.
Target Information
The protein encoded by this gene is proteolytically processed to release a secreted peptide termed endothelin 1.
This peptide is a potent vasoconstrictor and is produced by vascular endothelial cells.
Endothelin 1 also can affect the central nervous system.
Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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