Thermo Fisher Scientific Desmoplakin Monoclonal Antibody (DP-2.15)
Desmoplakin 1/2 단백질을 인식하는 Mouse Monoclonal Antibody (Clone DP-2.15). WB, IHC(F), ICC/IF 등 다양한 응용 가능. Human, Mouse, Rat 등 여러 종에 반응. Protein A 정제, 1 mg/mL 농도, 장기 보관 시 -20°C 권장.
- 판매단위
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Applications
- Western Blot (WB): Assay-dependent
- Immunohistochemistry (Frozen) (IHC (F)): Assay-dependent
- Immunocytochemistry (ICC/IF): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Chicken, Human, Mouse, Rat |
| Host/Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | DP-2.15 |
| Immunogen | Native bovine desmoplakin 1 and 2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | <0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2261943 |
Product Specific Information
Mouse anti Desmoplakin 1/2 antibody, clone DP-2.15 recognizes both desmoplakin 1 and 2 from stratified epithelia, simple epithelia including glands, urothelium, thymic reticular epithelium, hepatocytes, intercalated disks of myocardium, and arachnoid cells of meninges.
이 항체는 primary 및 metastatic carcinoma 검출에도 사용될 수 있습니다.
Target Information
Desmoplakin (DSP)은 데스모좀의 주요 고분자 단백질로, 데스모좀 내 cadherin-plakoglobin 복합체를 세포막 영역으로 조직화하고 intermediate filament를 데스모좀에 고정하는 역할을 합니다.
Desmoplakin 변이는 Keratoderma 및 cardiomyopathy와 관련되어 있습니다.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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