Thermo Fisher Scientific NCAPD2 Polyclonal Antibody
NCAPD2 단백질을 인식하는 Rabbit Polyclonal 항체로, Western Blot에 적합합니다. 인간에 반응하며, 합성 펩타이드 면역원으로 제작되었습니다. 고순도 친화 크로마토그래피 정제 제품으로, -20°C 보관이 권장됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.2–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the C-terminal of human NCAPD2 (aa 1279–1328) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2607791 |
Product Specific Information
Peptide sequence:
KAIIDEFEQK LRACHTRGLD GIKELEIGQA GSQRAPSAKK PSTGSRYQPLSequence homology:
Dog: 79%; Horse: 93%; Human: 100%; Pig: 92%; Rabbit: 92%
Target Information
Regulatory subunit of the condensin complex, required for conversion of interphase chromatin into mitotic-like condensed chromosomes. The condensin complex introduces positive supercoils into relaxed DNA and converts nicked DNA into positive knotted forms in the presence of topoisomerases. It may target the condensin complex to DNA via its C-terminal domain and promote resolution of double-strand DNA catenanes between sister chromatids. Condensin-mediated compaction increases tension, aiding in chromatid decatenation. Plays an essential role in neurogenesis by ensuring accurate mitotic chromosome condensation in neuron stem cells, affecting neuron pool and cortex size. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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