Thermo Fisher Scientific RNASE3 Monoclonal Antibody (5G4)
Human RNASE3 단백질을 인식하는 Mouse IgG1 단일클론 항체로 Western blot, IHC, ICC, Flow cytometry에 사용 가능. 단백질 G 정제, 2 mg/mL 농도, PBS/glycerol/BSA buffer에 저장. 연구용으로만 사용.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific RNASE3 Monoclonal Antibody (5G4)
Thermo Fisher Scientific RNASE3 Monoclonal Antibody (5G4)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:50–1:100 |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5G4 |
| Immunogen | Recombinant protein within Human Ribonuclease 3 aa 8–140 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol, 0.2% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2848837 |
Product Specific Information
Positive Control: U937, HeLa, SHG-44, human spleen tissue, human kidney tissue.
Target Information
ECP (eosinophil cationic protein), also known as RNS3 or RNASE3 (ribonuclease, RNase A family, 3), is a 160 amino acid potent cytotoxic secretory protein that belongs to the pancreatic ribonuclease family.
ECP localizes to the granule matrix of eosinophils and is involved in the immune response system. It acts as a cytotoxin, neurotoxin, and helminthotoxin secreted by activated human eosinophils.
ECP exhibits anti-parasitic, antibacterial, and ribonucleolytic activities. It has been associated with the neurotoxic Gordon phenomenon, characterized by ataxia, muscular rigidity, paralysis, and tremor.
ECP is a marker of eosinophilic inflammation and is elevated in active asthma and other allergic diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 없음)
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.