Thermo Fisher Scientific HLA-ABC Monoclonal Antibody (11C2)
Human HLA-ABC 단백질을 인식하는 mouse monoclonal antibody로, Western blot 및 IHC(P)에서 검증됨. 고순도 Affinity chromatography 정제, 2 mg/mL 농도의 액상 시약. PBS/glycerol buffer에 보관되며 연구용으로 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 11C2 |
| Immunogen | Recombinant protein within Human HLA Class I ABC (aa 1–362) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol, 0.2% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20 °C, avoid freeze/thaw cycles, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2848833 |
Product Specific Information
Positive Control: HeLa, rat uterus tissue, human kidney tissue, mouse testis tissue.
Target Information
HLA-class I major histocompatibility (MHC) antigens are intrinsic membrane glycoproteins expressed on nucleated cells and noncovalently associated with an invariant beta2 microglobulin. They carry foreign determinants important for immune recognition by cytotoxic T cells, thus playing a key role in antiviral and antitumor defense.
Human HLA-class I antigens are represented by HLA-A, HLA-B, and HLA-C molecules.
HLA and MHC antibodies are essential in Immunopeptidomics, enabling identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem mass spectrometry.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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