Thermo Fisher Scientific ASGR1 Polyclonal Antibody
Thermo Fisher Scientific ASGR1 Polyclonal Antibody는 마우스 ASGPR1 단백질을 인식하는 염소 유래 IgG 항체로, Western blot 및 중화 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS와 trehalose로 보존됩니다. 연구용으로만 사용 가능합니다.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific ASGR1 Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 0.25 µg/mL
Neutralization (Neu)
- Tested Dilution: Assay-Dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant mouse ASGPR1 (Ser60–Asn284) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2608934 |
Product Specific Information
- Reconstitute at 0.2 mg/mL in sterile PBS.
- Endotoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.
Target Information
The asialoglycoprotein receptor (ASGPR) is a 42 kDa transmembrane glycoprotein that mediates binding, internalization, and degradation of extracellular glycoproteins with exposed terminal galactose residues.
It is expressed on hepatocyte surfaces in a polar manner—present on sinusoidal and lateral plasma membranes but absent on bile canalicular membranes.
Mammalian hepatic ASGPR mediates endocytosis and degradation of serum proteins lacking terminal sialic residues.
The rat ASGPR consists of three subunits: RHL-1, RHL-2, and RHL-3.
Monoclonal antibody 8D7 recognizes a subunit-specific epitope of RHL-1 in rat ASGPR and shows cross-reactivity with human ASGPR.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.