Thermo Fisher Scientific NPAT Polyclonal Antibody
NPAT 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, IP 등 다양한 응용 가능. 1 mg/mL 액상 형태로 제공되며 4°C에서 보관. 세포 주기 조절 및 히스톤 유전자 발현 연구에 적합.
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Thermo Fisher Scientific NPAT Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:1,000–1:5,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000–1:5,000 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1377 and 1427 of human Nuclear Protein, Ataxia-Telangiectasia Locus (NPAT, UniProt ID: Q14207-1, NCBI Node ID: 9606) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC: Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections
- Based on 100% sequence identity, this antibody is predicted to react with Mouse
Target Information
NPAT is required for progression through the G1 and S phases of the cell cycle and for S phase entry. It activates transcription of histone H2A, H2B, H3, and H4 genes in conjunction with MIZF, and positively regulates ATM, MIZF, and PRKDC promoters. Transcriptional activation may involve recruitment of the NuA4 histone acetyltransferase (HAT) complex to target gene promoters.
Usage Notes
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송/결제/교환/반품 안내
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