Thermo Fisher Scientific GCR2/SGT1 Polyclonal Antibody
Thermo Fisher Scientific의 GCR2/SGT1 Polyclonal Antibody는 인간 단백질에 반응하는 토끼 IgG 기반 항체로, WB 및 IP 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 안정적인 액상 형태로 제공되어 연구용 단백질 분석에 신뢰성을 제공합니다.
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- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
- Publications: (참조 없음)
Immunoprecipitation (IP)
- Tested Dilution: 2–5 µg/mg lysate
- Publications: (참조 없음)
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 450 and 500 of Human Suppressor of GCR2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt.
Target Information
Regulator of p53/TP53 stability and function. Inhibits MDM2-mediated degradation of p53/TP53 possibly by cooperating in part with TXNIP (PubMed:16849563, PubMed:23880345).
May be involved in transcriptional regulation. In vitro, has intrinsic transactivation activity enhanced by EP300.
May act as a transcriptional activator required for expression of glycolytic genes (PubMed:19919181, PubMed:9928932).
Involved in regulation of cell cycle progression and proposed to disrupt Rb-E2F binding, leading to transcriptional activation of E2F proteins (PubMed:19640839).
Its cell cycle–regulating function may depend on RUVBL1-mediated association with the R2TP complex (PubMed:26711270).
May play a role in regulation of pre-mRNA splicing (PubMed:24722212).
[UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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