Thermo Fisher Scientific beta Amyloid (1-42) Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

-

View 8 publications 8 publications

Immunohistochemistry (IHC)

Assay-dependent

View 20 publications 20 publications

Immunohistochemistry (Paraffin) (IHC (P))

-

View 3 publications 3 publications

Immunohistochemistry (PFA fixed) (IHC (PFA))

-

View 1 publication 1 publication

Immunohistochemistry (Frozen) (IHC (F))

-

View 3 publications 3 publications

Immunohistochemistry - Free Floating (IHC (Free))

-

View 3 publications 3 publications

Immunocytochemistry (ICC/IF)

-

View 2 publications 2 publications

ELISA (ELISA)

1 µg/mL

View 2 publications 2 publications

Immunoprecipitation (IP)

-

View 1 publication 1 publication

Functional Assay (Functional)

Assay-dependent

-

Radioimmune Assays (RIA)

Assay-dependent

-

in situ PLA (PLA)

-

View 1 publication 1 publication

Dot blot (DB)

Assay-dependent

-

Immunomicroscopy (IM)

-

View 1 publication 1 publication

Miscellaneous PubMed (Misc)

-

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human

Published species

Human, Mouse, Non-human primate

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide derived from amino acids 36-42 within the C-terminal region of human beta-Amyloid protein if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Amyloid beta 42,uniProtId:P05067-1,ncbiNodeId:9606,antigenRange:36-42,antigenLength:770,antigenImageFileName:44-344_Amyloid_beta_42_P05067-1_Rabbit.svg,antigenImageFileNamePDP:44-344_Amyloid_beta_42_P05067-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2533636

Product Specific Information

Reacts with human Abeta42. No significant cross-reactivity to Abeta40 has been observed. Previous lots have shown no cross reactivity to Abeta43. Cross-reactivity against Abeta42 from mouse, rat, pig, cow, sheep, dog, rabbit, frog and polar bear (100% homology) is expected but has not been tested. The antibody has been used in ELISA. Previous lots of this antibody have been used in dot blots, RIA, and other related assays.

Target Information

Beta amyloid is a 40-43 amino acid peptide cleaved from amyloid precursor protein by a protease, gamma-secretase. Beta Amyloid (1-40) (Amyloid beta 40 or Abeta 40) together with beta Amyloid (1-42) (Amyloid beta 42 or Abeta 42) are two major C-terminal variants of the amyloid beta protein, constituting the majority of amyloid beta proteins. Both the Amyloid beta 40 and Amyloid beta 42 alloforms are major components of the extracellular plaques found in Alzheimer`s disease brain tissue.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.