Thermo Fisher Scientific beta Amyloid (1-40) Polyclonal Antibody
Human beta-Amyloid (1-40)에 특이적인 Rabbit Polyclonal Antibody로, WB, IHC, ELISA 등 다양한 응용에 적합. Beta-Amyloid (1-42)와 교차 반응 없음. 항원 친화 크로마토그래피로 정제된 액상 형태이며, -20°C에서 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | - | View 5 publications |
| Immunohistochemistry (IHC) | Assay-dependent | View 10 publications |
| Immunohistochemistry (Frozen) (IHC (F)) | - | View 3 publications |
| Immunohistochemistry - Free Floating (IHC (Free)) | - | View 1 publication |
| ELISA | 1 µg/mL | View 3 publications |
| Immunoprecipitation (IP) | - | View 1 publication |
| Radioimmune Assays (RIA) | Assay-dependent | - |
| Dot blot (DB) | Assay-dependent | - |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Bacteria, Cat, Human, Mouse, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Chemically synthesized peptide corresponding to amino acids 1–40 of human beta-Amyloid (Aβ) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2 |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2533599 |
Product Specific Information
No significant cross-reactivity to beta-Amyloid (1-42) has been observed. Previous lots of this antibody recognized the sequence of beta-Amyloid [1-40] in the region from amino acids 15–30. No blocking activity was observed with beta-Amyloid [1-12], whereas the peptides beta-Amyloid [14-35], beta-Amyloid [15-28], beta-Amyloid [17-30], and beta-Amyloid [1-40] were all able to block antibody activity.
Target Information
Beta-amyloid is a 40–43 amino acid peptide cleaved from amyloid precursor protein and a putative gamma-secretase. Amyloid beta (1-40) together with Amyloid beta (1-42) are two major C-terminal variants of the amyloid beta protein, constituting the majority of amyloid beta proteins. Both the amyloid beta (40) and amyloid beta (42) alloforms are major components of the extracellular plaques found in Alzheimer’s disease brain tissue.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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