Thermo Fisher Scientific beta Amyloid (1-40) Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

-

View 5 publications 5 publications

Immunohistochemistry (IHC)

Assay-dependent

View 10 publications 10 publications

Immunohistochemistry (Frozen) (IHC (F))

-

View 3 publications 3 publications

Immunohistochemistry - Free Floating (IHC (Free))

-

View 1 publication 1 publication

ELISA (ELISA)

1 µg/mL

View 3 publications 3 publications

Immunoprecipitation (IP)

-

View 1 publication 1 publication

Radioimmune Assays (RIA)

Assay-dependent

-

Dot blot (DB)

Assay-dependent

-

Product Specifications

Species Reactivity

Human

Published species

Bacteria, Cat, Human, Mouse, Non-human primate

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

The antiserum was produced against a chemically synthesized peptide corresponding to amino acids 1-40 of human beta-Amyloid (A-beta). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Amyloid beta 40,uniProtId:P05067-1,ncbiNodeId:9606,antigenRange:1-40,antigenLength:770,antigenImageFileName:44-136_Amyloid_beta_40_P05067-1_Rabbit.svg,antigenImageFileNamePDP:44-136_Amyloid_beta_40_P05067-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2

Contains

no preservative

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2533599

Product Specific Information

No significant cross-reactivity to beta-Amyloid 42 has been observed. Previous lots of this antibody recognized the sequence of beta-Amyloid [1-40] in the region from amino acids 15-30. No blocking activity was observed with beta-Amyloid [1-12] whereas the peptides beta-Amyloid [14-35], beta-Amyloid [15-28], beta-Amyloid [17-30] and Beta-Amyloid [1-40] were all able to block antibody activity.

Target Information

Beta-amyloid is a 40-43 amino acid peptide cleaved from amyloid precursor protein, and a putative gamma-secretase. Amyloid beta (1-40) together with Amyloid beta (1-42) are two major C-terminal variants of the amyloid beta protein, constituting the majority of amyloid beta proteins. Both the amyloid beta (40) and amyloid beta (42) alloforms are major components of the extracellular plaques found in Alzheimer`s disease brain tissue.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.