Thermo Fisher Scientific H3K79me2 Recombinant Rabbit Monoclonal Antibody (21H23L16)
H3K79me2 표적 Human 유래 Recombinant Rabbit Monoclonal 항체로, ICC/IF 및 ChIP assay에 최적화됨. 높은 특이성과 재현성을 제공하며, Protein A 정제 및 PBS buffer에 보관. Lot 간 일관성과 동물 유래 성분 없음.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 2 µg/mL |
| ChIP assay (ChIP) | 1.5 µg × 10⁶ cells |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 21H23L16 |
| Immunogen | Peptide corresponding to Human HIST1H3A (aa 76–84) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2633023 |
Product Specific Information
This antibody is predicted to react with Rat, Bat, Cat, and Pig.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. These systems are developed by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.
Advantages of recombinant rabbit monoclonal antibodies:
- High specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to larger rabbit immune repertoire
Target Information
Histone H3 is a DNA-binding protein found in the chromatin of all eukaryotic cells. Together with four core histone proteins, it binds DNA to form the nucleosome structure. Histones are central to transcription regulation, DNA repair, replication, and chromosomal stability.
Post-translational modifications of histones can alter chromatin structure or enable specific transcription factor binding. The N-terminal tail of histone H3 undergoes modifications such as methylation, acetylation, and phosphorylation, influencing various cellular processes.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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