Thermo Fisher Scientific STK11 Monoclonal Antibody (2A7-H2)

Applications

• ELISA (ELISA)
  • Tested Dilution: 10 µg/mL

Product Specifications

Product Specific Information

Sequence of this protein is as follows:
MEVVDPQQLG MFTEGELMSV GMDTFIHRID STEVIYQPRR KRAKLIGKYL MGDLLGEGSY GKVKEVLDSE TLCRRAVKIL KKKKLRRIPN GEANVKKEIQ LLRRLRHKNV IQLVDVLYNE EKQKMYMVME YCVCGMQEML DSVPEKRFPV CQAHGYFCQL IDGLEYLHSQ GIVHKDIKPG NLLLTTGGTL KISDLGVAEA LHPFAADDTC RTSQGSPAFQ PPEIANGLDT FSGFKVDIWS AGVTLYNITT GLYPFEGDNI YKLFENIGKG SYAIPGDCGP PLSDLLKGML EYEPAKRFSI RQIRQHSWFR KKHPPAEAPV PIPPSPDTKD RWRSMTVVPY LEDLHGADED EDLFDIEDDI IYTQDFTVPG QVPEEEASHN GQRRGLPKAV CMNGTEAAQL STKSRAEGRA PNPARKACSA SSKIRRLSAC KQQ

Target Information

LKB1 (also known as STK11 - Serine/threonine-protein kinase STK11) is a tumor suppressor belonging to the serine/threonine kinase family.
It physically associates with p53 and regulates specific p53-dependent apoptosis pathways.
LKB1 is present in both the cytoplasm and nucleus and translocates to mitochondria during apoptosis.
It functions as a master upstream protein kinase, regulating AMPK-related kinases and AMPK itself.
Mutations in the LKB1 gene are associated with Peutz-Jeghers syndrome.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.