Thermo Fisher Scientific STK11 Monoclonal Antibody (2A7-H2)
STK11 단백질을 표적하는 마우스 단일클론 항체로 인간 시료에 반응. ELISA에 적합하며 비결합형 액상 형태로 제공. 종양억제 단백질 LKB1 연구 및 AMPK 관련 경로 분석에 활용 가능. -20°C에서 보관.
- 판매단위
- pk
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Applications
- ELISA (ELISA)
- Tested Dilution: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2A7-H2 |
| Immunogen | STK11 (AAH07981, 1 a.a. ~ 433 a.a) full-length recombinant protein with GST tag (MW of GST tag alone: 26 KDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage Buffer | Ascites |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MEVVDPQQLG MFTEGELMSV GMDTFIHRID STEVIYQPRR KRAKLIGKYL MGDLLGEGSY GKVKEVLDSE TLCRRAVKIL KKKKLRRIPN GEANVKKEIQ LLRRLRHKNV IQLVDVLYNE EKQKMYMVME YCVCGMQEML DSVPEKRFPV CQAHGYFCQL IDGLEYLHSQ GIVHKDIKPG NLLLTTGGTL KISDLGVAEA LHPFAADDTC RTSQGSPAFQ PPEIANGLDT FSGFKVDIWS AGVTLYNITT GLYPFEGDNI YKLFENIGKG SYAIPGDCGP PLSDLLKGML EYEPAKRFSI RQIRQHSWFR KKHPPAEAPV PIPPSPDTKD RWRSMTVVPY LEDLHGADED EDLFDIEDDI IYTQDFTVPG QVPEEEASHN GQRRGLPKAV CMNGTEAAQL STKSRAEGRA PNPARKACSA SSKIRRLSAC KQQ
Target Information
LKB1 (also known as STK11 - Serine/threonine-protein kinase STK11) is a tumor suppressor belonging to the serine/threonine kinase family.
It physically associates with p53 and regulates specific p53-dependent apoptosis pathways.
LKB1 is present in both the cytoplasm and nucleus and translocates to mitochondria during apoptosis.
It functions as a master upstream protein kinase, regulating AMPK-related kinases and AMPK itself.
Mutations in the LKB1 gene are associated with Peutz-Jeghers syndrome.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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