Thermo Fisher Scientific DDX10 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:2,000–1:10,000

Immunoprecipitation (IP)

• Tested Dilution: 1–4 µg/mg lysate

Product Specifications

Product Specific Information

• Recommended shelf life: 1 year from date of receipt.

Target Information

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are involved in various cellular processes that alter RNA secondary structure, including translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly.
Some members are associated with embryogenesis, spermatogenesis, and cellular growth and division.
The DDX10 gene encodes a DEAD box protein potentially involved in ribosome assembly.
Fusion of this gene with the nucleoporin gene NUP98 (via inversion 11 (p15q22)) has been observed in patients with de novo or therapy-related myeloid malignancies.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.