Thermo Fisher Scientific SFRS15 Polyclonal Antibody
SFRS15 단백질을 인식하는 Rabbit Polyclonal 항체로, WB 및 ICC/IF에 사용 가능. 인간, 마우스, 랫트 반응성. 친화 크로마토그래피로 정제된 액상 항체이며, PBS와 50% 글리세롤에 보관. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human SCAF4 (Accession O95104), corresponding to amino acid residues G994–R1044 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2900524 |
Product Specific Information
Antibody detects endogenous levels of total SFRS15.
Target Information
The family of SR factors all contain one or more RNA recognition motifs (RRM) and an SR-rich domain. They are essential for constitutive splicing and regulate alternative splicing in a concentration-dependent manner.
Splicing factor arginine/serine-rich 15 (SFRS15), also known as CTD-binding SR-like protein RA4, contains one RRM and one SR-rich domain.
SFRS15 interacts with the C-terminal repetitive domain (CTD) of RNA polymerase II and is believed to link transcription and pre-mRNA processing both functionally and physically.
Localized to the nucleus, SFRS15 is expressed as two isoforms produced by alternative splicing.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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