Thermo Fisher Scientific ZNF265/ZIS Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:2,000–1:10,000

Immunoprecipitation (IP)

• Tested Dilution: Assay-dependent

Product Specifications

Product Specific Information

• Recommended shelf life: 1 year from date of receipt
• Based on 100% sequence identity, this antibody is predicted to react with Orangutan

Target Information

Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass transcriptional activation or repression.
ZNF265 (Zinc finger protein 265), also known as ZRANB2 (Zinc finger Ran-binding domain-containing protein 2), ZIS, ZIS1, or ZIS2, is a 330 amino acid protein belonging to the ZRANB2 family.
Localized to the nucleus, ZNF265 functions as a splicing factor responsible for alternatively splicing Tra-2 beta transcripts and may interfere with constitutive 5′-splice selection.
It contains two RanBP2-type zinc fingers that convey RNA-binding activity. Two isoforms, ZIS-1 and ZIS-2, are expressed due to alternative splicing events. Upon DNA damage, ZIS-2 may be phosphorylated by ATM or ATR.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

제품 이미지

(해당 제품 관련 항원 구조 이미지 등은 본문 하단에 배치됩니다.)