
Thermo Fisher Scientific ZNF265/ZIS Polyclonal Antibody
ZNF265/ZIS 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, Western blot과 Immunoprecipitation에 최적화. 인간 반응성, 액상 형태, 항원 친화 크로마토그래피로 정제. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–5 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 100 and 150 of Human zinc-finger protein 265 (zinc-finger, splicing) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, predicted to react with Mouse, Rat, Chicken, Pig, and Orangutan
Target Information
Zinc-finger proteins contain DNA-binding domains and have diverse functions, primarily involving transcriptional activation or repression.
ZNF265 (Zinc finger protein 265), also known as ZRANB2, ZIS, ZIS1, or ZIS2, is a 330-amino-acid protein belonging to the ZRANB2 family.
Localized to the nucleus, ZNF265 functions as a splicing factor responsible for alternative splicing of Tra-2 beta transcripts and may interfere with constitutive 5'-splice selection.
It contains two RanBP2-type zinc fingers mediating RNA-binding activity. Two isoforms (ZIS-1 and ZIS-2) arise from alternative splicing events, and ZIS-2 may be phosphorylated by ATM or ATR upon DNA damage.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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