Thermo Fisher Scientific ZNF265/ZIS Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:2,000–1:10,000

Immunoprecipitation (IP)

• Tested Dilution: 2–5 µg/mg lysate

Product Specifications

Product Specific Information

• Recommended shelf life: 1 year from date of receipt
• Based on 100% sequence identity, predicted to react with Mouse, Rat, Chicken, Pig, and Orangutan

Target Information

Zinc-finger proteins contain DNA-binding domains and have diverse functions, primarily involving transcriptional activation or repression.
ZNF265 (Zinc finger protein 265), also known as ZRANB2, ZIS, ZIS1, or ZIS2, is a 330-amino-acid protein belonging to the ZRANB2 family.
Localized to the nucleus, ZNF265 functions as a splicing factor responsible for alternative splicing of Tra-2 beta transcripts and may interfere with constitutive 5'-splice selection.
It contains two RanBP2-type zinc fingers mediating RNA-binding activity. Two isoforms (ZIS-1 and ZIS-2) arise from alternative splicing events, and ZIS-2 may be phosphorylated by ATM or ATR upon DNA damage.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

제품 이미지

(이미지 없음)