Thermo Fisher Scientific COQ3 Polyclonal Antibody
COQ3 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot, ICC/IF, ELISA에 적합합니다. Human, Mouse, Rat에서 반응하며, 고순도 Affinity 정제 및 PBS/glycerol buffer로 안정화되어 있습니다. 연구용으로 미토콘드리아 내막 단백질 검출에 활용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 50–369 of human COQ3 (NP_059117.3) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.74 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914678 |
Product Specific Information
Positive test controls include: HeLa, NCI-H460, MCF7, Mouse liver, Mouse brain, Mouse heart, Mouse kidney, Rat liver.
The target is usually found in the following locations: Matrix side, Mitochondrion inner membrane, Peripheral membrane protein.
Immunogen sequence:
PGVFNEYRTI WFKSYRTIFS CLNRIKSFRY PWARLYSTSQ TTVDSGEVKT FLALAHKWWD EQGVYAPLHS MNDLRVPFIR DNLLKTIPNH QPGKPLLGMK ILDVGCGGGL LTEPLGRLGA SVIGIDPVDE NIKTAQCHKS FDPVLDKRIE YRVCSLEEIV EETAETFDAV VASEVVEHVI DLETFLQCCC QVLKPGGSLF ITTINKTQLS YALGIVFSEQ IASIVPKGTH TWEKFVSPET LESILESNGL SVQTVVGMLY NPFSGYWHWS ENTSLNYAAY AVKSRVQEHP ASAEFVLKGE TEELQANACT NPAVHEKLKK
Target Information
Ubiquinone (coenzyme Q, or Q) is a critical component of the electron transport pathways of both eukaryotes and prokaryotes.
This lipid consists of a hydrophobic isoprenoid tail and a quinone head group, which anchors coenzyme Q to the membrane and enables its activity in the respiratory chain.
The S. cerevisiae COQ3 gene encodes an O-methyltransferase required for two steps in the biosynthetic pathway of coenzyme Q.
This enzyme methylates early and final intermediates, converting demethyl-ubiquinone to coenzyme Q.
The COQ3 gene product also methylates the prokaryotic early intermediate 2-hydroxy-6-polyprenyl phenol.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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