Thermo Fisher Scientific P2X7 Receptor Polyclonal Antibody, Atto 550

Applications

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:20

Immunohistochemistry (Frozen) (IHC (F))

• Tested Dilution: 1:100

Product Specifications

Product Specific Information

• Reconstitution: Add 50 µL double distilled water (DDW), depending on sample size.
• Ships as lyophilized powder at room temperature.
• Store upon arrival at -20°C.
• Reconstituted solution can be stored at 4°C for up to 1 week.
• For longer storage, aliquot and keep at -20°C.
• Avoid multiple freeze/thaw cycles.
• Centrifuge all antibody preparations before use (10,000 × g, 5 min).

Target Information

The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and mediates ATP-dependent lysis of macrophages by forming membrane pores permeable to large molecules. Activation by ATP in the cytoplasm may link cellular activity to changes in gene expression. Multiple alternatively spliced variants have been identified, most fitting nonsense-mediated decay criteria.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.