Thermo Fisher Scientific IL-22 Polyclonal Antibody, PeproTech
Human IL-22 단백질을 인식하는 Rabbit Polyclonal 항체로, Western Blot과 ELISA에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, -20°C에서 보관합니다. 연구용으로 IL-22 신호전달 및 염증 연구에 활용 가능합니다.
- 판매단위
- pk
카탈로그
3개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific IL-22 Polyclonal Antibody, PeproTech
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.1–0.2 µg/mL | — |
| ELISA (ELISA) | 0.5–2.0 µg/mL | 1 publication |
| Neutralization (Neu) | — | 1 publication |
| In vitro Assay (IV) | — | 1 publication |
| Miscellaneous PubMed (Misc) | — | 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E.coli-derived Recombinant Human IL-22 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.1–1.0 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient |
| RRID | AB_2929831 |
Product Specific Information
Amino Acid Sequence (Recombinant Human IL-22):
MAPISSHCRL DKSNFQQPYI TNRTFMLAKE ASLADNNTDV RLIGEKLFHG VSMSERCYLM KQVLNFTLEE VLFPQSDRFQ PYMQEVVPFL ARLSNRLSTC HIEGDDLHIQ RNVQKLKDTV KKLGESGEIK AIGELDLLFM SLRNACI.
Preparation:
Produced from sera of rabbits immunized with highly pure Recombinant Human IL-22. The anti-Human IL-22-specific antibody was purified by affinity chromatography using an immobilized Human IL-22 matrix.
Sandwich ELISA:
To detect Human IL-22 by sandwich ELISA (100 µL/well antibody solution), use 0.5–2.0 µg/mL of this antibody. In conjunction with PeproTech Biotinylated Anti-Human IL-22 (500-P211Bt) as the detection antibody, at least 0.2–0.4 ng/well of Recombinant Human IL-22 can be detected.
Western Blot:
For detection of Human IL-22 by Western Blot, use 0.1–0.2 µg/mL. With compatible secondary reagents, the detection limit is 1.5–3.0 ng/lane under both reducing and non-reducing conditions.
Target Information
IL-22 (Interleukin-22)
IL-22, also known as IL-10-related T-cell derived inducible factor, is an alpha-helical cytokine belonging to the IFN–IL-10 family, which includes IL-19, IL-20, IL-24, IL-26, IL-28, IL-29, and type I/II interferons. It is mainly produced by activated T cells and NK cells.
The IL-22 gene is located on chromosome 12q and is structurally related to IL-10. IL-22 acts through the heterodimeric receptor complex IL-22R1 and IL-10R2, activating the JAK-STAT pathway.
IL-22 primarily affects nonimmune cells such as epithelial cells of the skin, digestive, and respiratory systems, as well as hepatocytes and keratinocytes. It is an effector cytokine of the Th17 lineage, regulating genes associated with innate immunity and wound healing.
IL-22 is upregulated during chronic inflammation and plays a critical role in host defense and tissue repair.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.