Thermo Fisher Scientific Filamin 2 Polyclonal Antibody
Filamin 2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. WB, ICC/IF, ELISA 등 다양한 응용에 적합. 높은 특이성과 순도를 가진 액상 항체로, 인체 FLNC 단백질 연구에 활용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 2160–2340 of human FLNC (NP_0014493) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.01 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805220 |
Product Specific Information
Immunogen sequence:
IPGNWFQMVS AQERLTRTFT RSSHTYTRTE RTEISKTRGG ETKREVRVEE STQVGGDPFP AVFGDFLGRE RLGSFGSITR QQEGEASSQD MTAQVTSPSG KVEAAEIVEG EDSAYSVRFV PQEMGPHTVA VKYRGQHVPG SPFQFTVGPL GEGGAHKVRA GGTGLERGVA GVPAEFSIWT R
Positive Samples: A-549, LO2, NIH/3T3
Cellular Location: Cytoplasm, Membrane, Peripheral membrane protein, Z line, cytoskeleton, myofibril, sarcomere
Target Information
This gene encodes one of three related filamin genes, specifically gamma filamin. Filamin proteins crosslink actin filaments into orthogonal networks in cortical cytoplasm and participate in anchoring membrane proteins to the actin cytoskeleton. Three functional domains exist in filamin:
- N-terminal filamentous actin-binding domain
- C-terminal self-association domain
- Membrane glycoprotein-binding domain
Two transcript variants encoding different isoforms have been identified for this gene.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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