Thermo Fisher Scientific FMNL1 Polyclonal Antibody
FMNL1 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, Western blot 및 ELISA에 적합합니다. 인간과 생쥐 시료에 반응하며, 세포막 및 세포질 위치의 단백질 검출에 유용합니다. 고순도 친화 크로마토그래피 정제 제품입니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 900–1070 of human FMNL1 (NP_005883.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.78 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805214 |
Product Specific Information
Immunogen sequence:
DLHFLDKAGS VSLDSVLADV RSLQRGLELT QREFVRQDDC MVLKEFLRAN SPTMDKLLAD SKTAQEAFES VVEYFGENPK TTSPGLFFSL FSRFIKAYKK AEQEVEQWKK EAAAQEAGAD TPGKGEPPAP KSPPKARRPQ MDLISELKRR QQKEPLIYES DRDGAIEDII T
Positive Samples: LO2, A-549, Mouse brain
Cellular Location: Cell membrane, Cell projection, Cytoplasm, Cytoplasmic vesicle, Lipid-anchor, bleb, cell cortex, phagosome
Target Information
The Formin-like protein 1 (FRL1) gene encodes a formin-related protein involved in morphogenesis, cytokinesis, and cell polarity. Formins are a conserved class of proteins expressed in all eukaryotes and contain DAD (diaphanous autoregulatory domain), FH2 (formin homology 2), and GBD/FH3 (Rho GTPase-binding / formin homology 3) domains. FRL1 is localized in the cytoplasm and is highly expressed in spleen, lymph node, and bone marrow cells. It may play roles in cell motility, macrophage survival, and cytoskeletal organization.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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