Thermo Fisher Scientific MRE11 Polyclonal Antibody
MRE11 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC 등 다양한 응용에 적합합니다. 인간 시료 반응성이 있으며, Protein G로 정제된 액상 형태입니다. DNA 이중가닥 절단 복구 연구에 유용합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 10 µg/mL |
| Immunocytochemistry (ICC/IF) | Assay-Dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a portion of human MRE11 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1076966 |
Product Specific Information
Suggested positive control: 293 whole cell lysate.
Target Information
MRE11 (double-strand break repair protein MRE11) is a component of the MRN complex. This complex plays a central role in double-strand break repair, DNA recombination, maintenance of telomere integrity, and meiosis. The complex possesses single-stranded endonuclease activity and double-strand-specific 3′–5′ exonuclease activity provided by MRE11. RAD50 binds DNA ends and holds them in close proximity. Mutations in the MRE11 gene may result in ataxia-telangiectasia-like disorder 1.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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