Thermo Fisher Scientific RAMP1 Polyclonal Antibody
RAMP1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, 인간·생쥐·랫드 시료에 반응합니다. Western blot에 적합하며, 고순도 친화 크로마토그래피로 정제되었습니다. PBS/50% glycerol 용액 형태로 제공되며 -20°C에서 보관합니다.
- 카탈로그번호
- PA5115823
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human RAMP1 (Accession O60894), corresponding to amino acid residues C82–L132 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2900457 |
Product Specific Information
Antibody detects endogenous levels of total RAMP1.
Target Information
The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs).
RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. They are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane.
CRLR can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed.
In the presence of RAMP1, CRLR functions as a CGRP receptor. RAMP1 is involved in terminal glycosylation, maturation, and presentation of the CGRP receptor to the cell surface.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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