
Thermo Fisher Scientific RASA4 Polyclonal Antibody
RASA4 단백질을 표적하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC(P)에서 검증됨. 인간과 마우스 반응성. 고순도 Affinity chromatography 정제, 1 mg/mL 농도, PBS + 50% glycerol 저장. 연구용 전용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
- References: N/A
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
- References: N/A
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human RASA4 (Accession O43374), corresponding to amino acid residues V671–L721 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2900460 |
Product Specific Information
Antibody detects endogenous levels of total RASA4.
Target Information
This gene encodes a member of the GAP1 family of GTPase-activating proteins that suppresses the Ras/mitogen-activated protein kinase pathway in response to Ca(2+).
Stimuli that increase intracellular Ca(2+) levels result in the translocation of this protein to the plasma membrane, where it activates Ras GTPase activity.
Consequently, Ras is converted from the active GTP-bound state to the inactive GDP-bound state and no longer activates downstream pathways that regulate gene expression, cell growth, and differentiation.
Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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