
Thermo Fisher Scientific NFATC3 Polyclonal Antibody
NFATC3 단백질을 인식하는 Thermo Fisher Scientific의 고트 폴리클로날 항체로, Western blot에 적합합니다. 인간 반응성이 있으며 개와 소에서도 반응 예측됩니다. 액상 형태로 제공되며 TBS buffer에 0.5% BSA 포함, -20°C 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 0.03–0.1 µg/mL
- Publications: [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide sequence C-HQELDAHEDDLQIN (NFATC3 aa 121–134, internal region near N-terminus) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2554484 |
Product Specific Information
- Predicted to react with dog and cow based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 1:16,000.
Target Information
This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance.
mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD).
When translation ends upstream from the last exon-exon junction, NMD degrades mRNAs containing premature stop codons.
This protein is located only in the cytoplasm and interacts with the functional homolog of yeast Upf2p to trigger mRNA decapping.
Multiple polyadenylation sites have been noted for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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