Thermo Fisher Scientific KRT16 Monoclonal Antibody (OTI2E6), TrueMAB
KRT16 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western blot 및 IHC(P) 실험에 적합합니다. 인간 및 랫트 반응성을 가지며, Lyophilized 형태로 제공됩니다. 연구용으로 세포 골격 단백질 분석에 활용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2E6 |
| Immunogen | Full length human recombinant protein of human KRT16 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
KRT16 is a member of the keratin gene family, which encodes intermediate filament proteins that maintain epithelial cell structural integrity.
Type I cytokeratins are acidic proteins paired with type II keratins and clustered on chromosome 17q12-q21.
KRT16 is coexpressed with keratin 14 in epithelial tissues such as the esophagus, tongue, and hair follicles.
Mutations in KRT16 are associated with type 1 pachyonychia congenita, non-epidermolytic palmoplantar keratoderma, and unilateral palmoplantar verrucous nevus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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