Thermo Fisher Scientific ME2 Polyclonal Antibody
Thermo Fisher Scientific ME2 Polyclonal Antibody는 인간 ME2 단백질을 인식하는 토끼 유래 IgG 항체입니다. Western blot 및 IHC(P) 실험에 적합하며, 고순도 항원 친화 크로마토그래피로 정제되었습니다. PBS 기반 완충액에 40% 글리세롤을 포함하고 있으며 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.04–0.4 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:20–1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ME2. Recombinant protein control fragment (Product #RP-88954). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2643835 |
Product Specific Information
Immunogen sequence:
KVISKPISEH KILFLGAGEA ALGIANLIVM SMVENGLSEQ EAQKKIWMFD KYGLLVKGRK AKIDSYQEPF THSAPESIPD TFEDAVNILK PSTIIGVAGA GRLFTPDVIR AMASINERPV IFALSNPTA
Highest antigen sequence identity to the following orthologs:
- Mouse: 83%
- Rat: 80%
Target Information
ME2 encodes a mitochondrial NAD-dependent malic enzyme, a homotetrameric protein that catalyzes the oxidative decarboxylation of malate to pyruvate. This gene has been previously weakly linked to Friedreich ataxia, though that condition is now known to result from mutation in a different gene. Certain SNP haplotypes of ME2 may increase risk for idiopathic generalized epilepsy. Alternatively spliced transcript variants encode different isoforms of this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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