
Thermo Fisher Scientific ITM2B Polyclonal Antibody
Human ITM2B 단백질을 인식하는 Rabbit Polyclonal Antibody로, ICC/IF 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS와 40% 글리세롤 버퍼에 보관됩니다. Alzheimer 및 관련 신경퇴행성 질환 연구용으로 사용됩니다.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human ITM2B (Product #RP-107855) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C (avoid freeze/thaw cycles) |
| Shipping Conditions | Wet ice |
| RRID | AB_2665197 |
Product Specific Information
- Immunogen sequence:
MVKVTFNSALA QKEAKKDEPK SGEEALIIPP DAVAVDCKDP DDVVPVGQRR A - Highest antigen sequence identity:
- Mouse: 94%
- Rat: 96%
Target Information
Amyloid precursor proteins are processed by beta-secretase and gamma-secretase to produce beta-amyloid peptides which form the characteristic plaques of Alzheimer disease.
This gene encodes a transmembrane protein processed at the C-terminus by furin or furin-like proteases to produce a small secreted peptide that inhibits beta-amyloid deposition.
Mutations extending the C-terminal end of the encoded protein are associated with familial British dementia and familial Danish dementia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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