Thermo Fisher Scientific LZTS1 Polyclonal Antibody
Human LZTS1 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot, IHC(P), ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관됩니다. 암 연구 및 세포 주기 조절 관련 연구에 유용합니다.
- 카탈로그번호
- PA552274
- 판매단위
- pk
카탈로그
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human LZTS1. Recombinant protein control fragment (Product #RP-89289). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.74 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2643656 |
Product Specific Information
Immunogen sequence:
TEVNAKASEI LGLKAQLKDT RGKLEGLELR TQDLEGALRT KGLELEVCEN ELQRKKNEAE LLREKVNLLE QELQELRAQA ALARDMGPPT FPEDVPALQR ELERLRAELR EERQGHDQMS SGFQHERLVW KE
Highest antigen sequence identity to the following orthologs:
- Mouse: 85%
- Rat: 86%
Target Information
This gene encodes a tumor suppressor protein that is ubiquitously expressed in normal tissues. In uveal melanomas, expression of this protein is silenced in rapidly metastasizing and metastatic tumor cells but remains normal in slowly metastasizing or nonmetastasizing tumor cells. This protein may play a role in cell-cycle control by interacting with the Cdk1/cyclinB1 complex. The gene is located on chromosomal region 8p22, and loss of heterozygosity (LOH) in the 8p arm is a common feature of many cancer types.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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