Thermo Fisher Scientific LZTS1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human LZTS1. Recombinant protein control fragment (Product #RP-89289). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:LZTS1,uniProtId:Q9Y250-1,ncbiNodeId:9606,antigenRange:403-534,antigenLength:596,antigenImageFileName:PA5-52274_LZTS1_Q9Y250-1_Rabbit.svg,antigenImageFileNamePDP:PA5-52274_LZTS1_Q9Y250-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.74 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2643656

Product Specific Information

Immunogen sequence: TEVNAKASEI LGLKAQLKDT RGKLEGLELR TQDLEGALRT KGLELEVCEN ELQRKKNEAE LLREKVNLLE QELQELRAQA ALARDMGPPT FPEDVPALQR ELERLRAELR EERQGHDQMS SGFQHERLVW KE

Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 86%.

Target Information

This gene encodes a tumor suppressor protein that is ubiquitously expressed in normal tissues. In uveal melanomas, expression of this protein is silenced in rapidly metastasizing and metastatic tumor cells but has normal expression in slowly metastasizing or nonmetastasizing tumor cells. This protein may have a role in cell-cycle control by interacting with the Cdk1/cyclinB1 complex. This gene is located on chromosomal region 8p22. Loss of heterozygosity (LOH) in the 8p arm is a common characteristic of many types of cancer.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.