Thermo Fisher Scientific NEUROG2 Monoclonal Antibody (1D2)
인간 Neurogenin-2 단백질을 표적하는 Mouse IgG2b 단일클론 항체. ELISA에 적합하며, 액상 형태로 제공. -20°C에서 보관하며 방부제 무첨가. 신경발생 연구용으로 사용.
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Applications
- ELISA (ELISA)
Tested Dilution: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1D2 |
| Immunogen | NEUROG2 (NP_076924, 74 a.a. ~175 a.a) partial recombinant protein with GST tag (MW of GST tag alone: 26 KDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage Buffer | Ascites |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
CRPARLLGLV HDCKRRPSRA RAVSRGAKTA ETVQRIKKTR RLKANNRERN RMHNLNAALD ALREVLPTFP EDAKLTKIET LRFAHNYIWA LTETLRLADH CG
Target Information
Neurogenin-2 is a member of the neurogenin subfamily of basic helix-loop-helix (bHLH) transcription factor genes that play an important role in neurogenesis from migratory neural crest cells.
In mouse neurogenesis, Ngn2 and Ngn1 are expressed in distinct progenitor populations residing in the central and peripheral nervous systems. Mutation analyses demonstrate that Ngn1 is required for the determination of neuronal precursors for proximal cranial sensory ganglia, while Ngn2 is necessary for the determination of precursors for epibranchial placode-derived sensory neurons.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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