
Thermo Fisher Scientific PDE1A Polyclonal Antibody, Biotin
PDE1A 단백질을 인식하는 Biotin 결합 토끼 다클론 항체로, Western blot, IHC, ICC, ELISA, IP 등 다양한 응용에 적합합니다. 인산화 효소 신호전달 연구용으로 사용되며, 고순도 친화 크로마토그래피 정제 및 안정한 보관 용액 제공.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| Immunocytochemistry (ICC/IF) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
| Immunomicroscopy (IM) | 1:50–1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acid region 1–50 on PDE1A protein. Common to all PDE1A variants. |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20 °C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Cyclic nucleotide phosphodiesterases (PDEs) regulate intracellular cyclic nucleotide levels by hydrolyzing cAMP and/or cGMP to their corresponding nucleoside monophosphates. Members of the PDE1 family, including PDE1A, are Ca²⁺/calmodulin-dependent enzymes activated in the presence of Ca²⁺ (Michibata et al., 2001).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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