Thermo Fisher Scientific ZSCAN4 Monoclonal Antibody (OTI1E7), TrueMAB
인간 ZSCAN4 단백질(aa 164-433)을 인식하는 단일클론 항체로, Western blot에 적합합니다. 마우스 IgG1 형이며, 액상 형태로 1 mg/mL 농도입니다. 줄기세포 연구 및 유전체 안정성 관련 연구에 활용 가능합니다.
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Thermo Fisher Scientific ZSCAN4 Monoclonal Antibody (OTI1E7), TrueMAB
Applications
- Western Blot (WB)
Tested Dilution
- 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1E7 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 164–433 of human ZSCAN4 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Zygotic genome activation (ZGA) is the first and most critical transition event from the maternal genetic to the embryonic genetic program, occurring mainly at the late 2-cell stage.
ZSCAN4 encodes a SCAN domain and four zinc finger domains and is expressed in late 2-cell embryos and embryonic stem cells.
Loss-of-function studies using siRNA show delays in progression from the 2-cell to the 4-cell stage and subsequent embryo development.
ZSCAN4 plays an important role in preimplantation development and is involved in telomere maintenance and long-term genomic stability in embryonic stem cells, suggesting its critical role in maintaining pluripotency in replicating stem cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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