Thermo Fisher Scientific Phospho-CaMKII beta/gamma/delta (Thr287) Polyclonal Antibody
CaMKII 베타/감마/델타 단백질의 Thr287 인산화 형태를 특이적으로 인식하는 Rabbit Polyclonal 항체. Western blot 및 IHC(P) 검증 완료. 액상 형태로 제공되며, -20°C에서 보관. 연구용으로 세포 신호전달 및 인산화 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:1,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Published species | Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphopeptide derived from human CaMK2-beta/gamma/sigma around the phosphorylation site of Thr287 (Q-E-TP-V-E) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2556282 |
Target Information
The Ca²⁺/calmodulin-dependent protein kinases (CaM kinases) comprise a structurally related subfamily of serine/threonine kinases including CaMKI, CaMKII, and CaMKIV.
CaMKII is a ubiquitously expressed serine/threonine protein kinase activated by Ca²⁺ and calmodulin (CaM) and is implicated in the regulation of the cell cycle and transcription.
There are four CaMKII isozymes—alpha, beta, gamma, and delta—which may or may not be coexpressed in the same tissue type.
CaMKIV is stimulated by Ca²⁺ and CaM but also requires phosphorylation by a CaMK for full activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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