Thermo Fisher Scientific H4K5ac Polyclonal Antibody
Histone H4의 Lysine 5 아세틸화 형태를 인식하는 Rabbit Polyclonal Antibody. Western blot, ICC/IF, ELISA, IP, ChIP 등 다양한 응용 가능. 모든 종에 반응하며 연구용으로 적합. 장기 보관 시 -20°C에서 보관 권장.
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Thermo Fisher Scientific H4K5ac Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:600 |
| Immunocytochemistry (ICC/IF) | 1:400 |
| ELISA | 1:1,000 |
| Immunoprecipitation (IP) | Assay-dependent |
| ChIP assay (ChIP) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | All, Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Ovalbumin-conjugated peptide: NSGRGAcKGGKGLCc |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | <0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_931272 |
Product Specific Information
Rabbit anti-Histone H4 (Ac5) antibody recognizes Histone H4 when acetylated at lysine 5.
Target Information
Histones are basic nuclear proteins responsible for the nucleosome structure of chromosomal fiber in eukaryotes. Two molecules each of H2A, H2B, H3, and H4 form an octamer around which approximately 146 bp of DNA is wrapped, forming nucleosomes. The linker histone H1 interacts with linker DNA between nucleosomes and aids in chromatin compaction.
The histone H4 gene is intronless, encoding a member of the histone H4 family. Transcripts lack polyA tails but contain a palindromic termination element. This gene is located in the large histone gene cluster on chromosome 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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