Thermo Fisher Scientific IFN alpha Polyclonal Antibody
Human, Mouse, Rat 반응성의 Rabbit Polyclonal IFN alpha 항체로 Western blot, IHC, ICC/IF에 사용 가능. 합성 펩타이드 유래 면역원 기반, 액상 형태, 1 mg/mL 농도. 친화 크로마토그래피로 정제되어 높은 특이성과 재현성 제공. 연구용 전용 제품.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human IFNA1; IFNA13 (Accession P01562), corresponding to amino acid residues S21–F71 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2900066 |
Product Specific Information
Antibody detects endogenous levels of total Interferon alpha 1.
Target Information
IFN alpha (Interferon alpha) is a Type I interferon belonging to a family of structurally related, species-specific proteins found in vertebrates. Interaction with its receptor activates signaling pathways involved in innate immune responses against viral infection.
In humans, the IFN alpha gene is located on chromosome 9 and includes 14 different alpha isoforms along with beta, omega, epsilon, and kappa isoforms. Homologous molecules exist in many species including rats, mice, birds, reptiles, and fish.
Produced primarily by plasmacytoid dendritic cells, IFN alpha plays a key role in antiviral defense and modulation of adaptive immunity. Dysregulation is associated with diseases such as Hepatitis C and Hepatitis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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