
Thermo Fisher Scientific NAPRT1 Monoclonal Antibody (CL0665)
Human NAPRT1 단백질을 인식하는 Mouse IgG1 단일클론 항체. Western blot 및 IHC(Paraffin) 실험에 적합. Protein A로 정제된 액상 형태로 공급되며, 고순도 및 높은 특이성을 제공. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:200–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CL0665 |
| Immunogen | Recombinant protein corresponding to Human NAPRT1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.0 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2637233 |
Product Specific Information
- Immunogen sequence:
PAFFEHLRAL DCSEVTVRAL PEGSLAFPGV PLLQVSGPLL VVQLLETPLL CLVSYASLVA TNAARLRLIA GP - Highest antigen sequence identity to orthologs: Mouse – 97%, Rat – 96%
- Binds to an epitope located within the peptide sequence PAFFEHLRALDCSEV as determined by overlapping synthetic peptides
Target Information
Nicotinic acid (NA; niacin) is converted by nicotinic acid phosphoribosyltransferase (NAPRT; EC 2.4.2.11) to NA mononucleotide (NaMN), which is then converted to NA adenine dinucleotide (NaAD), and finally to nicotinamide adenine dinucleotide (NAD). NAD serves as a coenzyme in cellular redox reactions and is essential for various metabolic processes including cellular stress response (Hara et al., 2007).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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