Thermo Fisher Scientific ELOVL1 Polyclonal Antibody
ELOVL1 단백질을 인식하는 토끼 폴리클로날 항체로, Western blot에 최적화되어 있습니다. 인간, 마우스, 랫트 시료에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. 장기 보관 시 -20°C에서 냉동 보관이 권장됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 104–156 of Human ELOVL1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2719124 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is >95% as determined by SDS-PAGE.
Target Information
Elongation of very long chain fatty acid-like (ELOVL) proteins 1–6 are members of the ELO family of proteins, which play an important role in tissue-specific biosynthesis of very long chain fatty acids and sphingolipids.
ELOVL proteins act as catalysts in fatty acid elongation and localize to the endoplasmic reticulum (ER).
ELOVL1, also referred to as Ssc1, is the human homolog of the yeast ELO3 protein. It is expressed in various tissues, especially in stomach, skin, intestine, kidney, and lung.
ELOVL1 participates in the elongation of very long chain saturated and monounsaturated fatty acids (up to 26 carbons) and may be required for epithelial and skin barrier development. It is also important for myelin formation in the central nervous system.
Impaired ELOVL1 activity may be associated with disorders of sphingolipid metabolism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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