Thermo Fisher Scientific MYBPC2 Polyclonal Antibody
Rabbit polyclonal antibody against MYBPC2 for Western blot and IHC applications. Reacts with human and mouse samples. Purified by antigen affinity chromatography and supplied as a liquid at 1 mg/mL in PBS with sodium azide. Recommended positive control...
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1–2 µg/mL | View 1 publication |
| Immunohistochemistry (IHC) | 5 µg/mL | – |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 15 amino acid peptide near the carboxy terminus of human MYBPC2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at –20°C. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11154456 |
Product Specific Information
A suggested positive control is mouse skeletal muscle tissue lysate.
PA5-20917 can be used with blocking peptide PEP-1031.
Target Information
The MYBPC2 gene belongs to the myosin-binding protein C family, which includes fast-, slow-, and cardiac-type isoforms. These proteins are myosin-associated and located in the C region of A bands in striated muscle. MYBPC2 encodes the fast-type isoform.
Mutations in slow-type and cardiac-type isoforms are associated with distal arthrogryposis type 1 and hypertrophic cardiomyopathy. MYBPC2-related diseases include Lethal Congenital Contracture Syndrome 4 and Nemaline Myopathy 9.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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