Thermo Fisher Scientific ELOVL7 Polyclonal Antibody
ELOVL7 단백질을 인식하는 토끼 폴리클로날 항체로, Western blot과 IHC에 사용 가능. 인간 및 생쥐 반응성. 항원 친화 크로마토그래피로 정제되었으며, PBS 내 0.02% sodium azide 포함. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1 µg/mL |
| Immunohistochemistry (IHC) | 5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 15 amino acid peptide near the amino terminus of human ELOVL7 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at -20°C. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11152322 |
Product Specific Information
- Suggested positive control: human liver tissue lysate
- PA5-20913 can be used with blocking peptide PEP-1027
Target Information
Lipogenesis is a key event in the energy storage system and is controlled by the transcription factor sterol regulatory element-binding protein (SREBP)-1.
Elongation of very long chain fatty acids protein 7 (ELOVL7) is a member of the fatty acyl-CoA elongase gene family that elongates saturated very-long-chain fatty acids (SVLFA, C20:0-) and has been suggested to be involved in prostate cancer growth through saturated long-chain fatty acid metabolism.
The metabolic pathways of long-chain fatty acids play an important role in maintaining membrane lipid composition and generating cell signaling precursor molecules such as eicosanoids and sphingosine-1 phosphate.
Overexpression of ELOVL7 results in lipid accumulation in differentiated adipocytes; its expression is regulated by microRNA miR-219.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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