Thermo Fisher Scientific GCP4 Polyclonal Antibody
Human GCP4 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC(P), ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며 PBS+40% 글리세롤에 보존. 단기 4°C, 장기 -20°C 보관 권장. 연구용 전용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human GCP4. Recombinant protein control fragment (Product #RP-98070) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2641924 |
Product Specific Information
Immunogen sequence:
ILFVGESVQM FENQNVNLTR KGSILKNQED TFAAELHRLK QQPLFSLVDF EQVVDRIRST VAEHLWKLMV EESDLLGQLK IIKDFYLLGR GELFQAFIDT AQHMLKTPPT A
Highest antigen sequence identity to the following orthologs:
- Mouse: 100%
- Rat: 99%
Target Information
The gamma-Tubulin complex is composed of gamma Tubulin and the gamma-Tubulin complex-associated proteins GCP2, GCP3, GCP4, GCP5, and GCP6, all of which are essential components of microtubule organizing centers. These components localize to both the centrosome and cytoplasm, participating in microtubule nucleation and organization.
GCP4 (gamma-Tubulin complex component 4), also known as TUBGCP4, is a ubiquitously expressed 667 amino acid protein that localizes to the metaphase spindle during mitosis. Upon proteasome inhibition, GCP4 accumulates at the pericentriolar material, contributing to microtubule organization and nucleation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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