Thermo Fisher Scientific ABCA7 Polyclonal Antibody
ABCA7 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클론 항체로, Western blot과 IHC(Paraffin) 실험에 적합합니다. 인간, 생쥐, 랫트 반응성을 가지며, 고순도 항원 친화 크로마토그래피로 정제된 액상 형태입니다. 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
- Publications: [References not provided]
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
- Publications: [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues in Human ABCA7 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2719638 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is >95% as determined by SDS-PAGE.
Target Information
ATP-binding cassette (ABC) transporters are an evolutionarily conserved family that use ATP hydrolysis to catalyze the transport of various molecules across cell membranes. They are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White).
ABCA7, a member of the ABC1 subfamily, is a full-size ABC transporter consisting of two sets of multiple membrane-spanning domains plus the Walker motifs for ATP interaction. ABCA7 shows the highest homology to ABCA1, an essential molecule for cholesterol homeostasis.
High expression levels of ABCA7 in peripheral leukocytes, thymus, spleen, and bone marrow suggest a role in immune system lipid homeostasis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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