Thermo Fisher Scientific BAG2 Polyclonal Antibody
BAG2 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 폴리클로날 항체. Western blot에 적합하며 인간 및 돼지 시료에서 반응. 합성 펩타이드 면역원 사용, 액상 형태로 제공되며 -20°C 보관. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 0.1–0.3 µg/mL
- Publications: 없음
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Pig |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (CSKTLQQNAESRFN) corresponding to the C-terminus amino acids of BAG2 (aa 199–211) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_10981651 |
Product Specific Information
- This antibody is predicted to react with bovine and porcine based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 8,000.
Target Information
BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release.
All BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions.
The predicted BAG2 protein contains 211 amino acids.
The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells.
All three proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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