Thermo Fisher Scientific LRIG1 Polyclonal Antibody
Human, Mouse, Rat에서 반응하는 LRIG1 폴리클로날 항체로, Western blot, IHC, ICC, ELISA 등에 사용 가능. Protein A로 정제된 1 mg/mL 액상 제품이며, -20°C 보관. 종양 억제 단백질 LRIG1 연구용으로 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:200 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human LRIG1 (amino acids 1001–1093) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
LRIG1 protein (UniProt ID: Q96JA1) is encoded by a gene located on chromosome band 3p14.3, a region frequently deleted in various human cancers. LRIG1 is regarded as a tumor suppressor gene and encodes an integral cell-surface membrane protein expressed in specific human tissues. The 143-kDa LRIG1 protein may be cleaved into 111-kDa and 32-kDa fragments. LRIG1 is believed to inhibit the growth of glial cell tumors, and its downregulation may contribute to tumor development and progression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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