Thermo Fisher Scientific SOX10 Recombinant Mouse Monoclonal Antibody (rSOX10, 1074)
SOX10 단백질을 인식하는 마우스 재조합 단클론 항체로 인간 및 마우스 시료에 반응. Western blot, IHC, Peptide array 등 다양한 응용 가능. 고순도 Protein A/G 정제, 보존제 무첨가 PBS 용액 형태. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 2–4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1–2 µg/mL |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG1, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | rSOX10, 1074 |
| Immunogen | Recombinant human SOX10 protein fragment (around aa115–269) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | −20°C or −80°C if preferred |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- For immunohistochemistry (PFA fixed): incubate antibody for 30 minutes at room temperature.
- Formalin-fixed tissue staining requires heating sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 minutes at 95°C, followed by cooling at room temperature for 20 minutes.
Target Information
SOX10 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in embryonic development and cell fate determination.
It may act as a transcriptional activator after forming complexes with other proteins and functions as a nucleocytoplasmic shuttle protein.
SOX10 plays a key role in neural crest and peripheral nervous system development.
Mutations are associated with Waardenburg-Shah and Waardenburg-Hirschsprung diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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