Thermo Fisher Scientific SLC1A6 (extracellular) Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:200-1:500

-

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Peptide (C)TRTIVRTDNGSE, corresponding to amino acid residues 205-216 of rat EAAT4 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:EAAT4,uniProtId:O35921-1,ncbiNodeId:10114,antigenRange:205-216,antigenLength:561,antigenImageFileName:PA5-77428_EAAT4_O35921-1_Rabbit.svg,antigenImageFileNamePDP:PA5-77428_EAAT4_O35921-1_Rabbit_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

0.8 mg/mL

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2736605

Product Specific Information

Product is shipped at room temperature as a lyophilized powder and should be stored at -20 °C upon receipt. Reconstitution: add 50 µL of deionized water.

Target Information

Slc1a6 encodes a protein that is a glutamate transporters, also known as excitatory amino acid transporters (EAATs), are sodium- and potassium-dependent members of the solute carrier family 6 (SLC1), widely distributed throughout the brain. There are five EAAT subtypes, each with a specific distribution. Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. Slc1a6 functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion. Slc1a6 also mediates Cl(-) flux that is not coupled to amino acid transport and this avoids the accumulation of negative charges due to aspartate and Na(+) symport. Further, Slc1a6 [lays a redundant role in the rapid removal of released glutamate from the synaptic cleft, which is essential for terminating the postsynaptic action of glutamate (Probable). Diseases associated with SLC1A6 include Dicarboxylic Aminoaciduria.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.