Thermo Fisher Scientific CTNNBL1 Polyclonal Antibody
CTNNBL1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, IP 등 다양한 응용에 적합. 인간 및 생쥐 반응성. 항원 친화 크로마토그래피로 정제된 액상 항체로, 4°C 보관.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:100–1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1 and 50 of human catenin, beta like 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC, epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections
- Based on 100% sequence identity, antibody is predicted to react with Rat and Bovine
Target Information
The protein encoded by CTNNBL1 is a component of the pre-mRNA-processing factor 19-cell division cycle 5-like (PRP19-CDC5L) complex, which activates pre-mRNA splicing and is an integral part of the spliceosome. It functions as a nuclear localization sequence binding protein, interacts with activation-induced deaminase, and plays a role in antibody diversification. This gene may also be associated with obesity development. Alternative splicing produces multiple transcript variants, and a pseudogene exists on the X chromosome.
Diseases associated with CTNNBL1 include Immunodeficiency 99 with Hypogammaglobulinemia and Autoimmune Cytopenias.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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