
Thermo Fisher Scientific LIPG Monoclonal Antibody (OTI1B8), TrueMAB
LIPG 단백질을 인식하는 Mouse monoclonal antibody로 Western blot, IHC, ICC, Flow cytometry, IP에 사용 가능. Human 시료 반응성. Lyophilized 형태로 제공되며 PBS buffer에 8% trehalose 포함. 연구용으로 HDL 대사 관련 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
| Immunoprecipitation (IP) | 2 µg/500 µL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1B8 |
| Immunogen | Full length human recombinant protein of human LIPG produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, it is recommended to perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
LIPG (Lipase G, Endothelial type) is an endothelial lipase and a member of the lipoprotein lipase gene family. It is synthesized by endothelial cells and functions locally at the site of synthesis.
LIPG plays a physiological role in modulating lipoprotein metabolism. Overexpression of LIPG reduces HDL cholesterol levels, while LIPG deficiency increases HDL levels in animals.
It possesses phospholipase activity and may be involved in lipoprotein metabolism and vascular biology.
LIPG is a carboxyl esterase that hydrolyzes high-density lipoproteins, emulsifies triglycerides, and is essential for efficient digestion of dietary fats. It can also bind to heparin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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