Thermo Fisher Scientific C1orf86 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human C1orf86. Recombinant protein control fragment (Product #RP-94374). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:C1orf86,uniProtId:Q6NZ36-1,ncbiNodeId:9606,antigenRange:108-180,antigenLength:180,antigenImageFileName:PA5-58555_C1orf86_Q6NZ36-1_Rabbit.svg,antigenImageFileNamePDP:PA5-58555_C1orf86_Q6NZ36-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2638951

Product Specific Information

Immunogen sequence: GGHLESPARS LPQRPAPDPC RAPRVEQQPS VEGAAALRSC PMCQKEFAPR LTQLDVDSHL AQCLAESTED VTW

Highest antigen sequence identity to the following orthologs: Mouse - 58%, Rat - 55%.

Target Information

C1orf86 is a component of the Fanconi anemia (FA) complex required to recruit the FA complex to DNA interstrand cross-links (ICLs) and promote ICLs repair. Following DNA damage recognizes and binds Lys-63-linked ubiquitin generated by RNF8 at ICLs and recruits other components of the FA complex. It promotes translesion synthesis via interaction with REV1.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.