Thermo Fisher Scientific SBF1 Polyclonal Antibody
SBF1 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, Western blot에 적합합니다. 인간과 랫트 시료에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS/glycerol buffer에 보관하며 연구용으로만 사용됩니다.
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Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein of human SBF1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2720336 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is greater than 95% as determined by SDS-PAGE.
Target Information
SBF1 is a probable pseudophosphatase lacking several amino acids in the catalytic pocket, rendering it catalytically inactive. However, the pocket can still bind phosphorylated substrates and may protect them from phosphatases. It inhibits myoblast differentiation in vitro and induces oncogenic transformation in fibroblasts. According to PubMed:20937701, SBF1 may act as a guanine nucleotide exchange factor (GEF) activating RAB28, promoting GDP-to-GTP exchange and converting inactive GDP-bound Rab proteins into their active GTP-bound form.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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