Thermo Fisher Scientific JTB Polyclonal Antibody
JTB 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 적합합니다. Human 및 Rat 시료에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. 세포 분열 및 미토콘드리아 기능 연구에 활용 가능합니다.
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Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein of human JTB |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C (avoid freeze/thaw cycles) |
| Shipping Conditions | Wet ice |
| RRID | AB_2720335 |
Product Specific Information
This antibody was affinity-purified from rabbit antiserum using an epitope-specific immunogen. The purity is greater than 95% as determined by SDS-PAGE.
Target Information
JTB is required for normal cytokinesis during mitosis and plays a role in regulating cell proliferation. It may be a component of the chromosomal passenger complex (CPC), which ensures correct chromosome alignment and segregation and is essential for chromatin-induced microtubule stabilization and spindle assembly. JTB increases AURKB activity, inhibits TGFB1-induced apoptosis, and its overexpression can cause mitochondrial swelling and reduced membrane potential.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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